XM does not provide services to residents of the United States of America.

Sage Therapeutics' CFO to leave, drugmaker to lay off over 165 employees



<html xmlns="http://www.w3.org/1999/xhtml"><head><title>UPDATE 2-Sage Therapeutics' CFO to leave, drugmaker to lay off over 165 employees</title></head><body>

Adds details on CFO leaving company in paragraphs 1, 3 and background in paragraphs 8-10

Oct 17 (Reuters) -Sage Therapeutics SAGE.O said on Thursday its finance chief will leave the company and the drugmaker plans to lay off more than 165 employees as part of a reorganization plan that aims to focus on the launch of its postpartum depression pill.

The company's workforce reductions include about 55% of its research and development team, as well as changes to its top management.

Sage's Chief Financial Officer Kimi Iguchi will leave the company, while Chief Business Officer Chris Benecchi will take on the role of chief operating officer, the company said.

The drugmaker plans to prioritize the launch of its postpartum depression pill Zurzuvae, that has been jointly developed with Biogen BIIB.O.

Last year, the U.S. Food and Drug Administration approved Zurzuvae for postpartum depression but rejected it as a treatment for clinical depression, a much larger market.

Sage said on Thursday it will also focus on developing its experimental drug dalzanemdor for Huntington's disease, which causes nerve cells in the brain to decay over time.

The company forecast a non-recurring charge of about $26 million to $28 million associated with the reorganizations, that will primarily be incurred in the fourth quarter of 2024.

Sage expects to report data from a trial testing dalzanemdor as a treatment for Huntington's disease later this year.

Earlier this month, the drugmaker said it would stop developing dalzanemdor for Alzheimer's disease after it failed to meet the main goal of a late-stage trial.

The company previously stopped developing dalzanemdor as a treatment for Parkinson's disease.



Reporting by Sriparna Roy in Bengaluru; Editing by Shounak Dasgupta

</body></html>

Disclaimer: The XM Group entities provide execution-only service and access to our Online Trading Facility, permitting a person to view and/or use the content available on or via the website, is not intended to change or expand on this, nor does it change or expand on this. Such access and use are always subject to: (i) Terms and Conditions; (ii) Risk Warnings; and (iii) Full Disclaimer. Such content is therefore provided as no more than general information. Particularly, please be aware that the contents of our Online Trading Facility are neither a solicitation, nor an offer to enter any transactions on the financial markets. Trading on any financial market involves a significant level of risk to your capital.

All material published on our Online Trading Facility is intended for educational/informational purposes only, and does not contain – nor should it be considered as containing – financial, investment tax or trading advice and recommendations; or a record of our trading prices; or an offer of, or solicitation for, a transaction in any financial instruments; or unsolicited financial promotions to you.

Any third-party content, as well as content prepared by XM, such as: opinions, news, research, analyses, prices and other information or links to third-party sites contained on this website are provided on an “as-is” basis, as general market commentary, and do not constitute investment advice. To the extent that any content is construed as investment research, you must note and accept that the content was not intended to and has not been prepared in accordance with legal requirements designed to promote the independence of investment research and as such, it would be considered as marketing communication under the relevant laws and regulations. Please ensure that you have read and understood our Notification on Non-Independent Investment. Research and Risk Warning concerning the foregoing information, which can be accessed here.

Risk Warning: Your capital is at risk. Leveraged products may not be suitable for everyone. Please consider our Risk Disclosure.